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首页-小分子抑制剂&激动剂-Others-Other Targets-AER-271
AER-271

Chemical Structure : AER-271

CAS No.: 634913-39-6

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AER-271 (AER271)

货号: PC-36073Not For Human Use, Lab Use Only.

AER-271 (AER271) is a selective, small molecule inhibitor of aquaporin-4 (AQP4), the prodrug of AER-270 with enhanced solubility.

规格 价格 库存 数量
10 mg ￥980 In stock
25 mg ￥1580 In stock
50 mg ￥2580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AER-271 (AER271) is a selective, small molecule inhibitor of aquaporin-4 (AQP4), the prodrug of AER-270 with enhanced solubility.
AER-271 shows improved neurological outcome and reduced swelling in two models of CNS injury complicated by cerebral edema.

物理化学性质&存储条件

分子量 463.653
分子式 C15H9ClF6NO5P
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-{[3,5-Bis(trifluoromethyl) phenyl]carbamoyl}-4-chlorophenyl dihydrogen phosphate

参考文献

1. Farr GW, et al. Neuroscience. 2019 Feb 6. pii: S0306-4522(19)30054-5.

2. Wallisch JS, et al. Pediatr Res. 2018 Oct 26. doi: 10.1038/s41390-018-0215-5.

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