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AE1 inhibitor 22

Chemical Structure : AE1 inhibitor 22

CAS No.: 2728512-13-6

AE1 inhibitor 22

货号: PC-21411Not For Human Use, Lab Use Only.

AE1 inhibitor 22 is a small molecule inhibitor of the anion exchanger 1 transporter (AE1) with IC50 of 18 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

AE1 inhibitor 22 is a small molecule inhibitor of the anion exchanger 1 transporter (AE1) with IC50 of 18 uM.
Anion exchanger 1 (AE1), a member of the solute carrier (SLC) family, is the primary bicarbonate transporter in erythrocytes, regulating pH levels and CO2 transport between lungs and tissues.

物理化学性质&存储条件

分子量 429.46
分子式 C19H22F3N3O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-ethyl-5-(3-(3-(3-(trifluoromethyl)phenyl)propyl)ureido)benzenesulfonamide

参考文献

1. Capper MJ, et al. Nat Struct Mol Biol. 2023 Sep 7. doi: 10.1038/s41594-023-01085-6.

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