ADAR1 inhibitor H13

Chemical Structure : ADAR1 inhibitor H13

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货号: PC-27658Not For Human Use, Lab Use Only.

ADAR1 inhibitor H13 is potent, orally bioavailable ADAR1 modulator, exhibits potent antiproliferative activity against various cancer cell lines and selectively reduces ADAR1-mediated editing of APOBEC3D in a dose-dependent manner.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

ADAR1 inhibitor H13 is potent, orally bioavailable ADAR1 modulator, exhibits potent antiproliferative activity against various cancer cell lines and selectively reduces ADAR1-mediated editing of APOBEC3D in a dose-dependent manner.

物理化学性质&存储条件

分子量	287.68
分子式	C10H11ClFN5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,3S,5R)-5-(6-amino-2-fluoro-9H-purin-9-yl)-2-(chloromethyl)tetrahydrofuran-3-ol

参考文献

1. Wei A, et al. J Med Chem. 2026 Aug 13;69(15):18147-18161.