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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Matrix Metalloproteinase (MMP)-ADAMTS7 inhibitor 3a
ADAMTS7 inhibitor 3a

Chemical Structure : ADAMTS7 inhibitor 3a

CAS No.:

ADAMTS7 inhibitor 3a (Compound 3a)

货号: PC-22949Not For Human Use, Lab Use Only.

ADAMTS7 inhibitor 3a is a potent, selective ADAMTS7 inhibitor with Ki of 9 nM, 12-fold selective over ADAMTS5 (Ki=110 nM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ADAMTS7 inhibitor 3a is a potent, selective ADAMTS7 inhibitor with Ki of 9 nM, 12-fold selective over ADAMTS5 (Ki=110 nM).

物理化学性质&存储条件

分子量 561.58
分子式 C27H26F3N3O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-(1-Benzoylpiperidin-4-yl)-N-hydroxy-2-((4'-(trifluoromethyl) [1,1'-biphenyl])-4 sulfonamido)acetamide

参考文献

1. Cuffaro D, et al. RSC Med Chem. 2024 Jun 19;15(8):2806-2825.

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