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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Matrix Metalloproteinase (MMP)-ADAMTS-IN-1
ADAMTS-IN-1

Chemical Structure : ADAMTS-IN-1

CAS No.: 2688733-96-0

ADAMTS-IN-1

货号: PC-23034Not For Human Use, Lab Use Only.

ADAMTS-IN-1 is a potent dual inhibitor of ADAMTS-5 and ADAMTS-4 with IC50s of 8 and 12 nM, respectively, example 37-2 in Patent WO2021158626 A.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ADAMTS-IN-1 is a potent dual inhibitor of ADAMTS-5 and ADAMTS-4 with IC50s of 8 and 12 nM, respectively, example 37-2 in Patent WO2021158626 A.

物理化学性质&存储条件

分子量 424.32
分子式 C20H23Cl2N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(5S)-5-Cyclopropyl-5-[3-[(1R)-7,8-dichloro-1,2,4,5-tetrahydro-1-methyl-3H-3-benzazepin-3-yl]-3-oxopropyl]-2,4-imidazolidinedione

参考文献

1. Patent WO2021158626 A1.

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