ACP-5862 (ACP5862)

Chemical Structure : ACP-5862

CAS No.: 2230757-47-6

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货号: PC-49426Not For Human Use, Lab Use Only.

ACP-5862 (ACP5862) is a major metabolite of acalabrutinib and potent and selective covalent BTK inhibitor with IC50 of 5 nM.

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ACP-5862 (ACP5862) is a major metabolite of acalabrutinib and potent and selective covalent BTK inhibitor with IC50 of 5 nM.

分子量	481.516
分子式	C26H23N7O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(8-amino-3-(4-(but-2-ynamido)butanoyl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide

1. Terry Podoll, et al. J Pharmacol Exp Ther. 2022 Oct 30;JPET-AR-2022-001116.