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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-ACOU001
ACOU001

Chemical Structure : ACOU001

CAS No.: 2243284-38-8

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ACOU001 (ACOU 001)

货号: PC-49797Not For Human Use, Lab Use Only.

ACOU001 (ACOU 001) is a potent small-molecule agonist of Kv7.4 (KCNQ4) channel with potential effect against ge-related hearing loss (ARHL) and other hearing impairments related to compromised KV7.4 function.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    ACOU001 (ACOU 001) is a potent small-molecule agonist of Kv7.4 (KCNQ4) channel with potential effect against ge-related hearing loss (ARHL) and other hearing impairments related to compromised KV7.4 function.

    物理化学性质&存储条件

    分子量 377.77
    分子式 C12H9ClF5NOS2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (OC-6-21)-[4-[[[(5-Chloro-2-thienyl)carbonyl]amino]methyl]phenyl]pentafluorosulfur

    参考文献

    1. Patent WO2018158256 A2 Cyclic amides, acetamides and ureas useful as potassium channel openers

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