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首页-小分子抑制剂&激动剂-Others-Choline Kinase (ChoK)-ACG-548B
ACG-548B

Chemical Structure : ACG-548B

CAS No.: 795316-16-4

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ACG-548B (ACG548B)

货号: PC-60878Not For Human Use, Lab Use Only.

ACG-548B is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.12 uM, >400-fold selectivity over ChoKβ.

规格 价格 库存 数量
5 mg ￥1580 In stock
10 mg ￥2480 In stock
25 mg ￥3980 In stock
50 mg ￥5980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ACG-548B is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.12 uM, >400-fold selectivity over ChoKβ.
ACG-548B demonstrates in vitro antiproliferative activity against HT29 cells with IC50 of 2.08 uM.

物理化学性质&存储条件

分子量 777.426
分子式 C38H34Br2Cl2N4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1,1'-([1,1'-biphenyl]-3,3'-diylbis(methylene))bis(4-((4-chlorophenyl)(methyl)amino)pyridin-1-ium) bromide

参考文献

1. Lacal JC, et al. Mol Cancer Ther. 2015 Jan;14(1):31-9.

2. Patent US 20110178124 A1. Pyridinium and quinolinium derivatives.

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