ACG-416B | ChoKα inhibitor | Probechem Biochemicals

Chemical Structure : ACG-416B

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ACG-416B (ACG416B)

货号: PC-60877Not For Human Use, Lab Use Only.

ACG-416B (ACG416B) is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.13 uM, >385-fold selectivity over ChoKβ.

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生物&药学活性

ACG-416B (ACG416B) is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.13 uM, >385-fold selectivity over ChoKβ.
ACG-416B demonstrates in vitro antiproliferative activity against HT29 cells with IC50 of 1.94 uM.

物理化学性质&存储条件

分子量	708.542
分子式	C38H36Br2N4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1,1'-([1,1'-biphenyl]-3,3'-diylbis(methylene))bis(4-(methyl(phenyl)amino)pyridin-1-ium) bromide

参考文献

1. Lacal JC, et al. Mol Cancer Ther. 2015 Jan;14(1):31-9.

2. Patent US 20110178124 A1. Pyridinium and quinolinium derivatives.

ACG-416B (ACG416B)

生物&药学活性

物理化学性质&存储条件

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ACG-416B (ACG416B)

生物&药学活性

物理化学性质&存储条件

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