AC1-IN-38

Chemical Structure : AC1-IN-38

CAS No.: 2762422-55-7

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货号: PC-72951Not For Human Use, Lab Use Only.

AC1-IN-38 is a potent, selective inhibitor of adenylyl cyclase type 1 (AC1) with IC50 of 0.54 uM.

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5 mg	￥3280	In stock
10 mg	￥5280	In stock
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生物&药学活性

AC1-IN-38 is a potent, selective inhibitor of adenylyl cyclase type 1 (AC1) with IC50 of 0.54 uM.
AC1-IN-38 shows selectivity over a closely related isoform AC8, and no activity against AC2/5 and other common neurological targets.
AC1-IN-38 displayed modest antiallodynic effects in a mouse model of inflammatory pain.

物理化学性质&存储条件

分子量	355.373
分子式	C18H18FN5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(1-(4-ethyl-6-oxo-1,6-dihydropyrimidin-2-yl)-3-methyl-1H-pyrazol-5-yl)-2-fluoro-5-methylbenzamide

参考文献

1. Jason A. Scott, et al. Journal of Medicinal Chemistry. DOI: 10.1021/acs.jmedchem.1c01759

AC1-IN-38

生物&药学活性

物理化学性质&存储条件

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AC1-IN-38

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物理化学性质&存储条件

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