Vibilsertib (AC-003) | RIPK1 inhibitor | Probechem Biochemicals

Chemical Structure : AC-003

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AC-003 (Vibilsertib, AC003)

货号: PC-21572Not For Human Use, Lab Use Only.

Vibilsertib (AC-003) is a novel oral small-molecule inhibitor of receptor interacting protein kinase 1(RIPK1), inhibits necrosis and has the potential for treating idiopathic pulmonary fibrosis.

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生物&药学活性

Vibilsertib (AC-003) is a novel oral small-molecule inhibitor of receptor interacting protein kinase 1(RIPK1), effectively inhibits RIPK1-mediated necrosis and has the potential for treating idiopathic pulmonary fibrosis.

物理化学性质&存储条件

分子量	463.49
分子式	C24H25N5O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	tetrahydro-2H-pyran-4-yl 7-(2-(cyclopropanecarboxamido)imidazo[1,2-a]pyridin-6-yl)-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-1-carboxylate

参考文献

1. Patent WO2018237370 A1 2018-12-27 (Compound B19).

AC-003 (Vibilsertib, AC003)

生物&药学活性

物理化学性质&存储条件

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AC-003 (Vibilsertib, AC003)

生物&药学活性

物理化学性质&存储条件

参考文献

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