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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-ABT-925
ABT-925

Chemical Structure : ABT-925

CAS No.: 220519-06-2

ABT-925 (ABT925, A-437203, Lu201640)

货号: PC-20083Not For Human Use, Lab Use Only.

ABT-925 (A-437203) is a potent selective dopamine D3 receptor antagonist with Ki of 1.6 nM, 100-fold higher in vitro affinity for dopamine D3 versus D2 receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ABT-925 (A-437203) is a potent selective dopamine D3 receptor antagonist with Ki of 1.6 nM, 100-fold higher in vitro affinity for dopamine D3 versus D2 receptors.

物理化学性质&存储条件

分子量 456.53
分子式 C20H27F3N6OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((3-(4-(2-(tert-butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)propyl)thio)pyrimidin-4(3H)-one

参考文献

1. Graff-Guerrero A, et al. Int J Neuropsychopharmacol. 2010 Apr;13(3):273-87.

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