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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HCV-ABT-072
ABT-072

Chemical Structure : ABT-072

CAS No.: 1132936-00-5

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ABT-072 (ABT072)

货号: PC-62637Not For Human Use, Lab Use Only.

ABT-072 is a novel, orally bioavailable non-nucleoside HCV NS5B polymerase inhibitor with EC50 of 0.3 nM (GT1b).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    ABT-072 is a novel, orally bioavailable non-nucleoside HCV NS5B polymerase inhibitor with EC50 of 0.3 nM (GT1b).
    ABT-072 is a new direct-acting antivirals (DAAs) for the treatment of HCV infection.

    物理化学性质&存储条件

    分子量 469.556
    分子式 C24H27N3O5S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (E)-N-(4-(3-(tert-butyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxystyryl)phenyl)methanesulfonamide

    参考文献

    1. Randolph JT, et al. J Med Chem. 2018 Feb 8;61(3):1153-1163.

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