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首页-小分子抑制剂&激动剂-Tyrosine Kinase-c-Fms (CSF1R)-ABSK021
ABSK021

Chemical Structure : ABSK021

CAS No.: 2253123-16-7

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ABSK021 (Pimicotinib, ABSK-021)

货号: PC-22914Not For Human Use, Lab Use Only.

Pimicotinib (ABSK021) is a highly potent and selective, orally active inhibitor of CSF-1R with IC50 of 19.48 nM, shows significant pre-clinical anti-tumor activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Pimicotinib (ABSK021) is a highly potent and selective, orally active inhibitor of CSF-1R with IC50 of 19.48 nM, shows significant pre-clinical anti-tumor activity.

物理化学性质&存储条件

分子量 420.47
分子式 C22H24N6O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3,3-Dimethyl-N-(6-methyl-5-((2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl)oxy)pyridin-2-yl)-2-oxopyrrolidine-1-carboxamide

参考文献

1. Zhixuan Zhu, et al. Cancer Res (2022) 82 (12_Supplement): LB513.

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