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首页-小分子抑制剂&激动剂-Tyrosine Kinase-FGFR-ABSK011
ABSK011

Chemical Structure : ABSK011

CAS No.: 2230974-62-4

ABSK011 (Irpagratinib, ABSK 011)

货号: PC-21538Not For Human Use, Lab Use Only.

Irpagratinib (ABSK011) is a potent, selective FGFR4 inhibitor with strong antitumor activity against hepatocellular carcinoma (HCC).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Irpagratinib (ABSK011) is a potent, selective FGFR4 inhibitor with strong antitumor activity against hepatocellular carcinoma (HCC).

    物理化学性质&存储条件

    分子量 570.60
    分子式 C28H32F2N6O5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-[(3S,4S)-3-[[6-(2,6-Difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methyl-1-azetidinyl)pyrido[3,4-d]pyrimidin-2-yl]amino]tetrahydro-2H-pyran-4-yl]-2-propenamide

    参考文献

    1. Patent WO2018113584 A1.

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