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首页-小分子抑制剂&激动剂-Others-Other Targets-ABCA1 inducer 39
ABCA1 inducer 39

Chemical Structure : ABCA1 inducer 39

CAS No.: 2839627-76-6

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ABCA1 inducer 39

货号: PC-22962Not For Human Use, Lab Use Only.

ABCA1 inducer 39 is a nonlipogenic ABCA1-inducer (NLAI) with EC50 of 0.1 uM, increases ABCA1 expression, enhances APOE lipidation, and reverses multiple AD phenotypes, without increasing triglycerides (TG).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ABCA1 inducer 39 is a nonlipogenic ABCA1-inducer (NLAI) with EC50 of 0.1 uM, increases ABCA1 expression, enhances APOE lipidation, and reverses multiple AD phenotypes, without increasing triglycerides (TG).

物理化学性质&存储条件

分子量 587.48
分子式 C24H24Cl2N2O7S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

ethyl 3-chloro-5-(5-chloro-3-(N-(4-ethoxy-3-methoxyphenyl)-N-methylsulfamoyl)thiophene-2-carboxamido)benzoate

参考文献

1. Ganga Reddy Velma, Journal of Medicinal Chemistry August 27, 2024

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