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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-AAL(S)
AAL(S)

Chemical Structure : AAL(S)

CAS No.: 1823156-89-3

AAL(S) (PP2A activator AAL(S))

货号: PC-35654Not For Human Use, Lab Use Only.

AAL(S) is the chiral deoxy analog of the FDA approved drug FTY720, has been shown to inhibit proliferation and apoptosis in several cancer cell lines by activating protein phosphatase 2A (PP2A).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    AAL(S) is the chiral deoxy analog of the FDA approved drug FTY720, has been shown to inhibit proliferation and apoptosis in several cancer cell lines by activating protein phosphatase 2A (PP2A).

    物理化学性质&存储条件

    分子量 307.478
    分子式 C19H33NO2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-2-amino-2-methyl-4-(4-(octyloxy)phenyl)butan-1-ol

    参考文献

    1. Toop HD, et al. Org Biomol Chem. 2016 May 18;14(20):4605-16.

    2. Nair PM, et al. Allergy. 2017 Dec;72(12):1891-1903.

    3. Rahman MM, et al. Cell Signal. 2016 Apr;28(4):325-34.

    4. Rahman MM, et al. Sci Rep. 2015 May 18;5:10063.

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