AAK1 inhibitor 25A |CAS 2634715-17-4 Probechem Biochemicals

Chemical Structure : AAK1 inhibitor 25A

加入收藏

AAK1 inhibitor 25A

货号: PC-35961Not For Human Use, Lab Use Only.

AAK1 inhibitor 25A is a potent, selective inhibitor of AAK1 and the closely related kinase BMP2K with Ki of 8 nM (AAK1).

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

AAK1 inhibitor 25A is a potent, selective inhibitor of AAK1 and the closely related kinase BMP2K with Ki of 8 nM (AAK1).
AAK1 inhibitor 25A displays selectivity over the other members of the subfamily, Numb-associated kinases GAK and STK16, in a TR-FRET binding displacement assay.
AAK1 inhibitor 25A binds to BMP2K in live HEK293T cells with an IC50 of 602 nM.

物理化学性质&存储条件

分子量	396.465
分子式	C20H20N4O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(6-(3-(cyclopropanesulfonamido)phenyl)-1H-indazol-3-yl)cyclopropanecarboxamide

参考文献

1. Agajanian MJ, et al. Cell Rep. 2019 Jan 2;26(1):79-93.e8.