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首页-小分子抑制剂&激动剂-Others-Other Targets-AA92593
AA92593

Chemical Structure : AA92593

CAS No.: 457961-34-1

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AA92593 (AA 92593)

货号: PC-38201Not For Human Use, Lab Use Only.

AA92593 is a selective and competitive OPN4 (melanopsin) antagonist with IC50 of 665 nM.

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10 mg ￥980 In stock
25 mg ￥1680 In stock
50 mg ￥2680 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AA92593 is a selective and competitive OPN4 (melanopsin) antagonist with IC50 of 665 nM.
AA92593 attenuated melanopsin photocurrent in a dose-dependent manner, inhibited melanopsin photoresponses without inhibiting rod/cone function.
AA92593 reversibly attenuated melanopsin-mediated photoresponses.

物理化学性质&存储条件

分子量 269.359
分子式 C13H19NO3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-((4-methoxy-3-methylphenyl)sulfonyl)piperidine

参考文献

1. Kenneth A Jones, et al. Nat Chem Biol. 2013 Oct;9(10):630-5.

2. Qiushi Wang, et al. Mol Cancer Res. 2020 Jul;18(7):1028-1038.

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