Chemical Structure : AA41612
CAS No.: 433690-62-1
货号: PC-62204Not For Human Use, Lab Use Only.
AA 41612 is a potent, synthetic melanopsin antagonist with IC50 of 15.8 nM, attenuates melanopsin photocurrent in a dose-dependent manner.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥1280 | In stock | |
25 mg | ¥2180 | In stock | |
50 mg | ¥3580 | In stock | |
100 mg | Get quote |
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AA41612 is a selective and competitive OPN4 (melanopsin) antagonist with IC50 of 15.8 nM.
AA41612 attenuated melanopsin photocurrent in a dose-dependent manner, inhibited melanopsin photoresponses without inhibiting rod/cone function.
AA41612 reversibly attenuateed melanopsin-mediated photoresponses.
分子量 | 324.216 | |
分子式 | C12H15Cl2NO3S | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1-[(2,5-Dichloro-4-methoxyphenyl)sulfonyl]piperidine |
1. Jones KA, et al. Nat Chem Biol. 2013 Oct;9(10):630-5.
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