A779 | Angiotensin-(1-7) inhibitor | Probechem Biochemicals

Chemical Structure : A779

CAS No.: 159432-28-7

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A779 (A-779)

货号: PC-21224Not For Human Use, Lab Use Only.

A779 is a potent, selective antagonist of angiotensin-(1-7) receptor Mas, blocks the antidiuretic effect of Ang-(1-7) in vivo.

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10 mg	￥3580	In stock
25 mg	￥5880	In stock
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生物&药学活性

A779 is a potent, selective antagonist of angiotensin-(1-7) receptor Mas, blocks the antidiuretic effect of Ang-(1-7) in vivo.
A779 inhibited antidiuretic effect of Ang-(1-7) in water-loaded rats and the changes in blood pressure produced by Ang-(1-7) microinjection into the dorsal-medial and ventrolateral medulla.
A-779 did not change the dipsogenic, pressor, or myotropic effects of angiotensin II (Ang II).
A-779 did not affect the antidiuretic effect of vasopressin or the contractile effects of angiotensin III, bradykinin, or substance P on the rat ileum.

物理化学性质&存储条件

分子量	872.97
分子式	C39H60N12O11
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-L-Isoleucine-7-D-alanine-1-7-angiotensin II

参考文献

1. Santos RA, et al. Brain Res Bull. 1994;35(4):293-8.

A779 (A-779)

生物&药学活性

物理化学性质&存储条件

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A779 (A-779)

生物&药学活性

物理化学性质&存储条件

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