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首页-小分子抑制剂&激动剂-TGF-beta/Smad-TGF beta Receptor (TGFBR)-A 77-01
A 77-01

Chemical Structure : A 77-01

CAS No.: 607737-87-1

A 77-01 (A77-01, A-77-01)

货号: PC-45993Not For Human Use, Lab Use Only.

A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.

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10 mg ¥1280 In stock
25 mg ¥2180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.
A-77-01 is a close analogue of A-83-01(Axon 1421) and has a very similar biological profile of A-83-01.

物理化学性质&存储条件

分子量 286.3306
分子式 C18H14N4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Quinoline, 4-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-

参考文献

1. Tojo M, et al. Cancer Sci. 2005 Nov;96(11):791-800.

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