欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Sodium Channel-A-803467
A-803467

Chemical Structure : A-803467

CAS No.: 944261-79-4

加入收藏

A-803467 (A 803467, A803467)

货号: PC-42804Not For Human Use, Lab Use Only.

A-803467 (A803467) potent and selective Nav1.8 sodium channel blocker with IC50 of 8 nM.

规格 价格 库存 数量
25 mg ￥980 In stock
50 mg ￥1580 In stock
100 mg ￥2480 In stock
250 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A-803467 (A803467) is a potent and selective Nav1.8 sodium channel blocker with IC50 of 8 nM.
A-803467 displays >100-fold selectivity versus human Nav1.2, Nav1.3, Nav1.5, and Nav1.7 (IC50s>1 uM).
A-803467 potently blocks tetrodotoxin-resistant currents (IC50= 140 nM) and the generation of spontaneous and electrically evoked action potentials in vitro in rat dorsal root ganglion neurons.
A-803467 attenuates neuropathic and inflammatory pain in the rat.

物理化学性质&存储条件

分子量 357.7876
分子式 C19H16ClNO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-Furancarboxamide, 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)-

参考文献

1. Jarvis MF, et al. Proc Natl Acad Sci U S A. 2007 May 15;104(20):8520-5.

2. McGaraughty S, et al. J Pharmacol Exp Ther. 2008 Mar;324(3):1204-11.

3. Joshi SK, et al. J Pain. 2009 Mar;10(3):306-15.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: