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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-A-68930 hydrochloride
A-68930 hydrochloride

Chemical Structure : A-68930 hydrochloride

CAS No.: 130465-39-3

A-68930 hydrochloride (A68930)

货号: PC-63113Not For Human Use, Lab Use Only.

A-68930 is a potent, specific, orally bioavailable agonist of the D1 dopamine receptor (D1DR) with EC50 of 2.5 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    A-68930 is a potent, specific, orally bioavailable agonist of the D1 dopamine receptor (D1DR) with EC50 of 2.5 nM.
    A-68930 shows a much weaker agonist (EC50=3,920 nM) at the D2 dopamine receptor.
    A-68930 demonstrates antidepressant and anorectic effects in animal models without stimulant effects.

    物理化学性质&存储条件

    分子量 307.77
    分子式 C16H17NO3 · HCl
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1H-2-Benzopyran-5,6-diol, 1-(aminomethyl)-3,4-dihydro-3-phenyl-, hydrochloride, (1R,3S)-rel- (9CI)

    参考文献

    1. Kebabian JW, et al. Am J Hypertens. 1990 Jun;3(6 Pt 2):40S-42S.

    2. Trampus M, et al. Eur J Pharmacol. 1993 Apr 22;235(1):83-7.

    3. AI-Naser HA, et al. Behav Pharmacol. 1994 Apr;5(2):210-218.

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