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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-A-395N
A-395N

Chemical Structure : A-395N

CAS No.: 2096983-62-7

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A-395N (A395N)

货号: PC-62310Not For Human Use, Lab Use Only.

A-395N is the negative control compound of A-395, which is a potent, selective, and cellularly active PRC2 subunit EED inhibitor with Kd of 1.5 nM..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    A-395N is the negative control compound of A-395, which is a potent, selective, and cellularly active PRC2 subunit EED inhibitor with Kd of 1.5 nM.

    物理化学性质&存储条件

    分子量 442.62
    分子式 C24H34N4O2S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (3R,4S)-1-benzyl-N,N-dimethyl-4-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)pyrrolidin-3-amine

    参考文献

    1. He Y, et al. Nat Chem Biol. 2017 Apr;13(4):389-395.

    2. Cancer Discov. 2017 Apr;7(4):OF8. doi: 10.1158/2159-8290.CD-RW2017-030.

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