Elraglusib (9-ING-41) | GSK-3β inhibitor | Probechem Biochemicals

Chemical Structure : 9-ING-41

CAS No.: 1034895-42-5

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9-ING-41 (Elraglusib, 9ING41, 9-ING 41)

货号: PC-60431Not For Human Use, Lab Use Only.

Elraglusib (9-ING-41) is a novel potent, selective GSK-3β inhibitor with IC50 of 0.7 uM.

规格	价格	库存
5 mg	￥980	In stock
10 mg	￥1480	In stock
25 mg	￥2580	In stock
50 mg	￥4280	In stock
100 mg		Get quote

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生物&药学活性

Elraglusib (9-ING-41) is a novel potent, selective GSK-3β inhibitor with IC50 of 0.7 uM.
9-ING-41 demonstrates good antiproliferative activity against a panel of pancreatic cancer cell lines (IC50=0.5-5 uM), decreases XIAP expression and significantly induces apoptosis.
9-ING-41 affects energy homeostasis and induces autophagy, demonstrates tumor growth inhibition in vivo.

物理化学性质&存储条件

分子量	404.35
分子式	C22H13FN2O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(5-fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)-1H-pyrrole-2,5-dione

参考文献

1. Gaisina IN, et al. J Med Chem. 2009 Apr 9;52(7):1853-63.

2. Pal K, et al. Mol Cancer Ther. 2014 Feb;13(2):285-96.

3. Ugolkov A, et al. Cancer Lett. 2016 Oct 1;380(2):384-92.

4. Hilliard TS, et al. Anticancer Drugs. 2011 Nov;22(10):978-85.

9-ING-41 (Elraglusib, 9ING41, 9-ING 41)

生物&药学活性

物理化学性质&存储条件

参考文献

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9-ING-41 (Elraglusib, 9ING41, 9-ING 41)

生物&药学活性

物理化学性质&存储条件

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