8-Nitrotryptanthrin (GNF-PF-3777) | IDO2 inhibitor | Probechem Biochemicals

Chemical Structure : 8-Nitrotryptanthrin

CAS No.: 77603-42-0

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8-Nitrotryptanthrin (GNF-PF-3777, IDO2 inhibitor)

货号: PC-42226Not For Human Use, Lab Use Only.

8-Nitrotryptanthrin (GNF-PF-3777) is a potent human indoleamine 2,3-dioxygenase 2 (IDO2) inhibitor with Ki of 0.97 uM, also exhibits significant antitrypanosomal activities with EC50 of 0.82 uM.

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10 mg	￥2180	In stock
25 mg	￥3580	In stock
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生物&药学活性

8-Nitrotryptanthrin (GNF-PF-3777) is a potent human indoleamine 2,3-dioxygenase 2 (IDO2) inhibitor with Ki of 0.97 uM, also exhibits significant antitrypanosomal activities with EC50 of 0.82 uM.

物理化学性质&存储条件

分子量	293.2338
分子式	C15H7N3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: 6.4 mg/mL (Need warming)
Chemical Name/SMILES	Indolo[2,1-b]quinazoline-6,12-dione, 8-nitro-

参考文献

1. Li J, et al. Eur J Med Chem. 2016 Nov 10;123:171-179.

2. Scovill J, et al. Antimicrob Agents Chemother. 2002 Mar;46(3):882-3.

3. Hwang JM, et al. J Nat Prod. 2013 Mar 22;76(3):354-67.

8-Nitrotryptanthrin (GNF-PF-3777, IDO2 inhibitor)

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物理化学性质&存储条件

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8-Nitrotryptanthrin (GNF-PF-3777, IDO2 inhibitor)

生物&药学活性

物理化学性质&存储条件

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