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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI3K-740Y-P
740Y-P

Chemical Structure : 740Y-P

CAS No.: 1236188-16-1

740Y-P (740 Y-P, PDGFR 740Y-P)

货号: PC-25861Not For Human Use, Lab Use Only.

740Y-P (PDGFR 740Y-P, 740 Y-P) is a potent and cell-permeable PI3K activator/agonist, binds to SH2 domain of p85 regulatory subunit of PI3-kinase, induces iNOS expression and SGHPL-4 cell motility.

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5 mg ¥1980 In stock
10 mg ¥3280 In stock
25 mg ¥5480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

740Y-P (PDGFR 740Y-P, 740 Y-P) is a potent and cell-permeable PI3K activator/agonist, binds to SH2 domain of p85 regulatory subunit of PI3-kinase, induces iNOS expression and SGHPL-4 cell motility.

物理化学性质&存储条件

分子量 3270.70
分子式 C141H222N43O39PS3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

L-Serine, L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysyl-L-seryl-L-α-aspartylglycylglycyl-O-phosphono-L-tyrosyl-L-methionyl-L-α-aspartyl-L-methionyl-

参考文献

1. D Derossi, et al. Biochem Biophys Res Commun. 1998 Oct 9;251(1):148-52.

2. Cartwright JE, et al. Exp Cell Res. 2002 Oct 1;279(2):219-26.

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