710GO (EMBC-710GO)

Chemical Structure : 710GO

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货号: PC-26943Not For Human Use, Lab Use Only.

710GO (EMBC-710GO) is a potent, selective, orally available melanocortin receptor MC3R/MC4R dual agonist with EC50 of 0.073/0.042 nM respectively in cAMP signaling assays, induces significant weight loss in primates with diet-induced obesity.

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710GO (EMBC-710GO) is a potent, selective, orally available melanocortin receptor MC3R/MC4R dual agonist with EC50 of 0.073/0.042 nM respectively in cAMP signaling assays, induces significant weight loss in primates with diet-induced obesity.

物理化学性质&存储条件

分子量	1238.44
分子式	C60H84FN17O11
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,5R,8S,11S,14S,22S)-2-((1H-imidazol-4-yl)methyl)-11-((1H-indol-3-yl)methyl)-22-((S)-2-acetamidohexanamido)-N-((R)-1-((R)-2-carbamoylpyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)-8-(3-((diaminomethylene)amino)propyl)-5-(4-fluorobenzyl)-3,6,9,12,19,23-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-14-carboxamide

参考文献

1. Seiler JL, et al. Nat Commun. 2026 May 29;17(1):4808.

710GO (EMBC-710GO)

生物&药学活性

物理化学性质&存储条件

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710GO (EMBC-710GO)

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