7-alpha-hydroxycholesterol | TCR inhibitor | Probechem Biochemicals

Chemical Structure : 7-alpha-hydroxycholesterol

CAS No.: 566-26-7

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7-alpha-hydroxycholesterol (7a-HC)

货号: PC-22368Not For Human Use, Lab Use Only.

7alpha-hydroxycholesterol (7a-HC) is the 7alpha-hydroxy derivative of cholesterol, is a potent inhibitor of TCR signaling and promotes membrane binding of CD3ε cytoplasmic domain.

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5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3480	In stock
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100 mg		Get quote

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生物&药学活性

7alpha-hydroxycholesterol (7a-HC) is the 7alpha-hydroxy derivative of cholesterol, is a potent inhibitor of TCR signaling and promotes membrane binding of CD3ε cytoplasmic domain.

物理化学性质&存储条件

分子量	402.66
分子式	C27H46O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3S,7S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol

参考文献

1. Zhengxu Ren, et al. Cell Chem Biol. 2024 May 16;31(5):920-931.e6.

7-alpha-hydroxycholesterol (7a-HC)

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7-alpha-hydroxycholesterol (7a-HC)

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物理化学性质&存储条件

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