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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Nitric Oxide Synthase (NOS)-7-Nitroindazole (7-NI)
7-Nitroindazole (7-NI)

Chemical Structure : 7-Nitroindazole (7-NI)

CAS No.: 2942-42-9

7-Nitroindazole (7-NI)

货号: PC-23711Not For Human Use, Lab Use Only.

7-Nitroindazole (7-NI) is a selective and BBB-penatrable inhibitor of nNOS, inhibits the activity of central NOS with an IC50 of 0.47 μM in the cerebellum of mice, has anti-injurious and neuroprotective properties.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

7-Nitroindazole (7-NI) is a selective and BBB-penatrable inhibitor of nNOS, inhibits the activity of central NOS with an IC50 of 0.47 μM in the cerebellum of mice, has anti-injurious and neuroprotective properties.

物理化学性质&存储条件

分子量 163.14
分子式 C7H5N3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7-Nitro-1H-indazole

参考文献

1. Moore PK, et al. Br J Pharmacol. 1993 Feb;108(2):296-7.

2. Memarpour S, et al. 2020 Nov;45(11):2775-2785.

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