7-BIA |CAS:1313403-49-4 Probechem Biochemicals

Chemical Structure : 7-BIA

CAS No.: 1313403-49-4

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7-BIA (PTPRD inhibitor 7-BIA)

货号: PC-35733Not For Human Use, Lab Use Only.

7-BIA is a small molecule 7-butoxy illudalic acid analog that targets receptor-type protein tyrosine phosphatase D (PTPRD, IC50=1-3 uM) with some specificity.

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5 mg	￥3480	In stock
10 mg	￥5280	In stock
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生物&药学活性

7-BIA is a small molecule 7-butoxy illudalic acid analog that targets receptor-type protein tyrosine phosphatase D (PTPRD, IC50=1-3 uM) with some specificity.
7-BIA weakly inhibits PTPRS (IC50=40 uM), displays IC50>100 uM at any of many tested receptors, transporters, or sites of action of other drugs.
7-BIA reduces cocaine-conditioned place preference in mice without toxicity, 7-BIA provides a lead compound for addiction therapeutics.

物理化学性质&存储条件

分子量	294.303
分子式	C15H18O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	7-butoxy-3-hydroxy-6-methoxy-1-oxoisochromane-5-carbaldehyde

参考文献

1. Uhl GR, et al. Proc Natl Acad Sci U S A. 2018 Oct 22. pii: 201720446.

7-BIA (PTPRD inhibitor 7-BIA)

生物&药学活性

物理化学性质&存储条件

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7-BIA (PTPRD inhibitor 7-BIA)

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物理化学性质&存储条件

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