6-diazo-5-oxo-L-norleucine | Glutamine antagonist, Glutaminase inhibito

Chemical Structure : 6-diazo-5-oxo-L-norleucine

CAS No.: 157-03-9

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6-diazo-5-oxo-L-norleucine (DON, 6-Diazo-5-oxo-L-nor-Leucine)

货号: PC-25739Not For Human Use, Lab Use Only.

6-Diazo-5-oxo-L-norleucine (DON) is a gamma-glutamyl analog and glutamine antagonist, inhibits phosphate-activated glutaminase, shows anticancer activity and reduces the self-renewal potential and metastatic capacity of tumour cells.

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5 mg	￥2180	In stock
10 mg	￥3580	In stock
25 mg	￥5880	In stock
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100 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	171.16
分子式	C6H9N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES

参考文献

1. Shapiro RA, et al. Biochem J. 1982 Dec 1;207(3):561-6.

2. Wu F, et al. Anticancer Res. 1997 Jul-Aug;17(4A):2363-7.

3. Takeuchi H, et al. Exp Neurol. 2008 Nov;214(1):144-6.

6-diazo-5-oxo-L-norleucine (DON, 6-Diazo-5-oxo-L-nor-Leucine)

生物&药学活性

物理化学性质&存储条件

参考文献

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6-diazo-5-oxo-L-norleucine (DON, 6-Diazo-5-oxo-L-nor-Leucine)

生物&药学活性

物理化学性质&存储条件

参考文献

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