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首页-抗体药物偶连体和PROTACs-ADCs Linker/Click Chemistry-6-Maleimidohexanoic acid N-hydroxysuccinimide ester
6-Maleimidohexanoic acid N-hydroxysuccinimide ester

Chemical Structure : 6-Maleimidohexanoic acid N-hydroxysuccinimide ester

CAS No.: 55750-63-5

6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS)

货号: PC-45996Not For Human Use, Lab Use Only.

A heterobifunctional cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity.

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50 mg ¥1680 In stock
100 mg ¥2544.0 In stock
500 mg ¥7450 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A heterobifunctional cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity; a useful protective group in antibody drug conjugates.

物理化学性质&存储条件

分子量 308.2867
分子式 C14H16N2O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester

参考文献

1. Ehrlich GK, et al. Bioconjug Chem. 2013 Dec 18;24(12):2015-24.

2. Maeda M, et al. Bioorg Med Chem Lett. 2005 Feb 1;15(3):621-4.

3. Kida S, et al. Bioorg Med Chem Lett. 2006 Feb;16(3):743-5.

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