Chemical Structure : 5MPN
CAS No.: 47208-82-2
货号: PC-35343Not For Human Use, Lab Use Only.
PFKFB4 inhibitor 5MPN is a first-in-class, selective, competitive, orally available inhibitor of PFKFB4 with Ki of 8.6 uM, does not inhibit PFK-1 or PFKFB3.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥1880 | In stock | |
10 mg | ¥2980 | In stock | |
25 mg | ¥4780 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
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PFKFB4 inhibitor 5MPN is a first-in-class, selective, competitive, orally available inhibitor of PFKFB4 with Ki of 8.6 uM, does not inhibit PFK-1 or PFKFB3.
PFKFB4 inhibitor 5MPN suppresses the glycolysis and proliferation of multiple human cancer cell lines but not non-transformed epithelial cells in vitro.
PFKFB4 inhibitor 5MPN suppresses the glucose metabolism and growth of tumors in mice.
分子量 | 305.334 | |
分子式 | C15H19N3O4 | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
5-(n-(8-methoxy-4-quinolyl)amino)pentyl nitrate |
1. Chesney J, et al. Oncotarget. 2015 Jul 20;6(20):18001-11.
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