5MPN | PFKFB4 inhibitor | Probechem Biochemicals

Chemical Structure : 5MPN

CAS No.: 47208-82-2

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5MPN (PFKFB4 inhibitor 5MPN)

货号: PC-35343Not For Human Use, Lab Use Only.

PFKFB4 inhibitor 5MPN is a first-in-class, selective, competitive, orally available inhibitor of PFKFB4 with Ki of 8.6 uM, does not inhibit PFK-1 or PFKFB3.

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5 mg	￥1580	In stock
10 mg	￥2480	In stock
25 mg	￥4280	In stock
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100 mg		Get quote

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生物&药学活性

PFKFB4 inhibitor 5MPN is a first-in-class, selective, competitive, orally available inhibitor of PFKFB4 with Ki of 8.6 uM, does not inhibit PFK-1 or PFKFB3.
PFKFB4 inhibitor 5MPN suppresses the glycolysis and proliferation of multiple human cancer cell lines but not non-transformed epithelial cells in vitro.
PFKFB4 inhibitor 5MPN suppresses the glucose metabolism and growth of tumors in mice.

物理化学性质&存储条件

分子量	305.334
分子式	C15H19N3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(n-(8-methoxy-4-quinolyl)amino)pentyl nitrate

参考文献

1. Chesney J, et al. Oncotarget. 2015 Jul 20;6(20):18001-11.

5MPN (PFKFB4 inhibitor 5MPN)

生物&药学活性

物理化学性质&存储条件

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5MPN (PFKFB4 inhibitor 5MPN)

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物理化学性质&存储条件

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