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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Immune Checkpoints-5-OP-RU
5-OP-RU

Chemical Structure : 5-OP-RU

CAS No.: 2408493-91-2

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5-OP-RU

货号: PC-27782Not For Human Use, Lab Use Only.

5-OP-RU is a natural product formed during bacterial synthesis of vitamin B2, potently activates mucosal associated invariant T (MAIT) cells and has immunomodulatory, inflammatory, and anticancer properties, binds to histocompatibility complex (MHC)-related protein MR1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

5-OP-RU is a natural product formed during bacterial synthesis of vitamin B2, potently activates mucosal associated invariant T (MAIT) cells and has immunomodulatory, inflammatory, and anticancer properties, binds to histocompatibility complex (MHC)-related protein MR1.

物理化学性质&存储条件

分子量 330.30
分子式 C12H18N4O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-(((E)-2-Oxopropylidene)amino)-6-(((2R,3R,4S)-2,3,4,5-tetrahydroxypentyl)amino)pyrimidine-2,4(1H,3H)-dione

参考文献

1. Corbett AJ, et al. Nature. 2014 May 15;509(7500):361-5.

2. Wang H, et al. Sci Immunol. 2019 Nov 15;4(41):eaaw0402.

3. Legoux F, et al. Science. 2019 Oct 25;366(6464):494-499.

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