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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Immune Checkpoints-5-OE-RU
5-OE-RU

Chemical Structure : 5-OE-RU

CAS No.: 1610526-17-4

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5-OE-RU

货号: PC-27783Not For Human Use, Lab Use Only.

5-OE-RU is a natural product formed during bacterial synthesis of vitamin B2, potently activates mucosal associated invariant T (MAIT) cells and has immunomodulatory, inflammatory, and anticancer properties, binds to histocompatibility complex (MHC)-related protein MR1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

5-OE-RU is a natural product formed during bacterial synthesis of vitamin B2, potently activates mucosal associated invariant T (MAIT) cells and has immunomodulatory, inflammatory, and anticancer properties, binds to histocompatibility complex (MHC)-related protein MR1.

物理化学性质&存储条件

分子量 316.27
分子式 C11H16N4O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

D-Ribitol, 1-deoxy-1-[[1,2,3,6-tetrahydro-2,6-dioxo-5-[(2-oxoethylidene)amino]-4-pyrimidinyl]amino]-

参考文献

1. Corbett AJ, et al. Nature. 2014 May 15;509(7500):361-5.

2. Veerapen N, et al. Mol Immunol. 2021 Jan;129:114-120.

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