Chemical Structure : 5-NITP
货号: PC-62751Not For Human Use, Lab Use Only.
5-NITP is a non-natural nucleotide that inhibits ribonucleotide reductase (hRR) with IC50 of 170 uM, demonstrates anti-cancer effects against leukemia cells by altering cell-cycle progression.
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5-NITP is a non-natural nucleotide that inhibits ribonucleotide reductase (hRR) with IC50 of 170 uM, demonstrates anti-cancer effects against leukemia cells by altering cell-cycle progression.
分子量 | 518.2 | |
分子式 | C13H17N2O14P3 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Ahmad MF, et al. Mol Cancer Ther. 2012 Oct;11(10):2077-86.
2. Choi JS, et al. Cancer Res. 2018 Feb 15;78(4):1083-1096.
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