5-BDBD

Chemical Structure : 5-BDBD

CAS No.: 768404-03-1

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货号: PC-72721Not For Human Use, Lab Use Only.

5-BDBD is a potent and selective P2X4 receptor (P2X4R) antagonist, inhibits P2X4-mediated currents in CHO cells with IC50 of 0.5 uM.

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25 mg	￥2580	In stock
50 mg	￥3980	In stock
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生物&药学活性

5-BDBD is a potent and selective P2X4 receptor (P2X4R) antagonist, inhibits P2X4-mediated currents in CHO cells with IC50 of 0.5 uM.
5-BDBD displays no significant antagonist effects at other P2X receptors.
5-BDBD reduces long-term potentiation (LTP) in rat hippocampal slices.

物理化学性质&存储条件

分子量	355.191
分子式	C17H11BrN2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(3-bromophenyl)-1,3-dihydro-2H-benzofuro[3,2-e]-1,4-diazepin-2-one

参考文献

1. Wu T, et al. Am J Physiol Heart Circ Physiol. 2011 Jul;301(1):H69-78.

2. Balázs B, et al. Cell Physiol Biochem. 2013;32(1):11-24.

3. Barr TP, et al. Pain. 2014 Jun;155(6):1091-1101.

5-BDBD

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5-BDBD

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