4E2RCat | eIF4E/eIF4G inhibitor | Probechem Biochemicals

Chemical Structure : 4E2RCat

CAS No.: 432499-63-3

加入收藏

4E2RCat (eIF4E-eIF4G inhibitor)

货号: PC-42237Not For Human Use, Lab Use Only.

4E2RCat is a small molecule inhibitor of eIF4E-eIF4G interaction with IC50 of 13.5 uM in TR-FRET-based assay.

规格	价格	库存
5 mg	￥1680	In stock
10 mg	￥2380	In stock
25 mg	￥3980	In stock
50 mg	￥5980	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

4E2RCat is a small molecule inhibitor of eIF4E-eIF4G interaction with IC50 of 13.5 uM in TR-FRET-based assay.
4E2RCat inhibits cap-dependent translation in a dose-dependent manner, significantly decreases human coronavirus 229E (HCoV-229E) replication,.
4E2RCat reduces the percentage of infected cells and intra- and extracellular infectious virus titers.

物理化学性质&存储条件

分子量	455.9339
分子式	C22H14ClNO4S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: 15.5 mg/mL
Chemical Name/SMILES	Benzoic acid, 2-chloro-5-[5-[[4-oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]-2-furanyl]-

参考文献

1. Cencic R, et al. J Virol. 2011 Jul;85(13):6381-9.

2. Cencic R, et al. Proc Natl Acad Sci U S A. 2011 Jan 18;108(3):1046-51.

3. Bhat M, et al. Nat Rev Drug Discov. 2015 Apr;14(4):261-78.

4E2RCat (eIF4E-eIF4G inhibitor)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

4E2RCat (eIF4E-eIF4G inhibitor)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.