4BPPNit

Chemical Structure : 4BPPNit

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货号: PC-73362Not For Human Use, Lab Use Only.

4BPPNit is a small molecule significantly augmented glycosylation of α-dystroglycan, in part through upregulation of LARGE1 glycosyltransferase gene expression.

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生物&药学活性

4BPPNit is a small molecule significantly augmented glycosylation of α-dystroglycan, in part through upregulation of LARGE1 glycosyltransferase gene expression.
4BPPNit augments functional glycosylation of α‐dystroglycan in human FKRP‐iPSC‐derived neural stem cells.
4BPPNit induces upregulation of LARGE1 gene expression.

物理化学性质&存储条件

分子量	337.235
分子式	C14H13BrN2OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(4-bromophenyl)-6-ethylsulfanyl-2-oxo-3,4-dihydro-1H-pyridine-5-carbonitrile

参考文献

1. Jihee Kim, et al. EMBO Rep. 2019 Nov 5;20(11):e47967.

4BPPNit

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物理化学性质&存储条件

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4BPPNit

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