4-OH-DiPT

Chemical Structure : 4-OH-DiPT

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货号: PC-22529Not For Human Use, Lab Use Only.

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25 mg		Get quote
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100 mg		Get quote

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生物&药学活性

4-OH-DiPT is a synthetic 5-hydroxytryptamine 2A receptor (5-HT2A receptor) agonist with Ki of 0.12 uM, shows strongest agonist activity at all three 5-HT2A/2B/2C receptors with near full agonist activity at 5-HT2A.
4-OH-DiPT has comparable activity at mouse and human 5-HT2A/2B/2C receptors.
4-OH-DiPT significantly reduced freezing responses to conditioned cues in a dose-dependent manner with a greater potency in female mice than male mice.
4-OH-DiPT activates BLA interneurons via the 5-HT2A receptor to enhance GABAergic inhibition of BLA principal neurons.

物理化学性质&存储条件

分子量	260.38
分子式	C16H24N2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-hydroxy-N,N-diisopropyltryptamine

参考文献

1. Kelly TJ, et al. Neuropsychopharmacology. 2024 Apr;49(5):854-863.

2. Bryson N, et al. ACS Chem Neurosci. 2024 May 17. doi: 10.1021/acschemneuro.4c00058.

4-OH-DiPT

生物&药学活性

物理化学性质&存储条件

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4-OH-DiPT

生物&药学活性

物理化学性质&存储条件

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