4-Br-BnIm |CAS:1654775-71-9 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Heat Shock Protein (HSP)-4-Br-BnIm

Chemical Structure : 4-Br-BnIm

加入收藏

4-Br-BnIm

货号: PC-61032Not For Human Use, Lab Use Only.

4-Br-BnIm is a potent, subtype-selective Grp94 inhibitor with Kd of 0.96 uM, 13-fold selectivity over Hsp90α.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

4-Br-BnIm is a potent, subtype-selective Grp94 inhibitor with Kd of 0.96 uM, 13-fold selectivity over Hsp90α.
4-Br-BnIm facilitates mutant myocilin degradation and rescues phenotypes in a transgenic mouse model of hereditary primary open-angle glaucoma.

物理化学性质&存储条件

分子量	465.728
分子式	C20H18BrClN2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	methyl 2-(2-(1-(4-bromobenzyl)-1H-imidazol-2-yl)ethyl)-3-chloro-4,6-dihydroxybenzoate

参考文献

1. Stothert AR, et al. Sci Rep. 2017 Dec 20;7(1):17951.

2. Crowley VM, et al. J Med Chem. 2016 Apr 14;59(7):3471-88.

联系我们 sales@probechem.com

4-Br-BnIm

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

4-Br-BnIm

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.