3M-011 |CAS:642473-62-9 Probechem Biochemicals

Chemical Structure : 3M-011

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3M-011 (3M011;3M 854A)

货号: PC-70305Not For Human Use, Lab Use Only.

3M-011 is a potent TLR7/8 agonist and cytokine inducer.

规格	价格	库存	数量
25 mg		Get quote
100 mg		Get quote
500 mg		Get quote
1 g		Get quote

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生物&药学活性

3M-011 is a potent TLR7/8 agonist and cytokine inducer.
3M-011 stimulates type I interferon (IFN) and other cytokines such as TNF-alpha, IL-12, and IFN-gamma from rat peripheral blood mononuclear cells.
3M-011 induces IL-12 and COX-2 expression in mDC from HIV+ and HIV- individuals, and inhibits H3N2 influenza viral replication in the nasal cavity; potentiates NK cytotoxicity, and shows antitumor effects in scid/B6 mice and scid/NOD mice.

物理化学性质&存储条件

分子量	391.49
分子式	C18H25N5O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(1-(4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-yl)methanesulfonamide

参考文献

1. Martinson JA, et al. Cell Immunol. 2007 Nov-Dec;250(1-2):75-84.

2. Hammerbeck DM, et al. Antiviral Res. 2007 Jan;73(1):1-11.

3M-011 (3M011;3M 854A)

生物&药学活性

物理化学性质&存储条件

参考文献

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3M-011 (3M011;3M 854A)

生物&药学活性

物理化学性质&存储条件

参考文献

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