Chemical Structure : 3-Bromopyruvic acid
CAS No.: 1113-59-3
货号: PC-45777Not For Human Use, Lab Use Only.
A glycolytic inhibitor that inhibits hexokinase II activity, suppresses ATP production, and induces endoplasmic reticulum (ER) stress.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 g | ¥480 | In stock | |
10 g | ¥640 | In stock | |
25 g | ¥1280 | In stock |
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A glycolytic inhibitor that inhibits hexokinase II activity, suppresses ATP production, and induces endoplasmic reticulum (ER) stress; potentiates acetate-induced apoptosis and anti-proliferative effect in CRC cells; abrogates MUC1-mediated radiation resistance both in vitro and in vivo pancreatic cancer models, by reducing glucose flux into nucleotide biosynthetic pathways and enhancing DNA damage.
分子量 | 166.9581 | |
分子式 | C3H3BrO3 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
H2O: ≥ 32 mg/mL |
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Chemical Name/SMILES |
Propanoic acid, 3-bromo-2-oxo- |
1. Can Z, et al. Anticancer Drugs. 2017 Aug;28(7):739-749.
2. Ferro S, et al. Oncotarget. 2016 Sep 21. doi: 10.18632/oncotarget.12156.
3. Gunda V, et al. Clin Cancer Res. 2017 Jul 18. pii: clincanres.1151.2017.
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