2G272

Chemical Structure : 2G272

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货号: PC-26379Not For Human Use, Lab Use Only.

2G272 is a smll molecule calcium (Ca2+) influx inducer, triggers store-operated Ca2+ entry (SOCE) in mBMDC as well as increases in CD80 and CD86 surface expression.

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生物&药学活性

2G272 is a smll molecule calcium (Ca2+) influx inducer, triggers store-operated Ca2+ entry (SOCE) in mBMDC as well as increases in CD80 and CD86 surface expression.
2G272 enhances antigen presenting cell stimulated T cell proliferation.
2G272 promotes the release of immune-stimulatory EVs from mBMDCs. 2G272 does not stimulate systemic cytokine release in vivo.
2G272 elicits Th2 biased immune responses in a murine model.

物理化学性质&存储条件

分子量	444.38
分子式	C15H15N3O4S2Se
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl 2-(benzo[c][1,2,5]selenadiazole-4-sulfonamido)-4,5-dimethylthiophene-3-carboxylate

参考文献

1. Yokoyama Y, et al. Front Immunol. 2026 Feb 17;17:1704416.

2. Sako Y, et al. ACS Chem Biol. (2023) 18:982–93.

2G272

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2G272

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物理化学性质&存储条件

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