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首页-小分子抑制剂&激动剂-GPCR-Free Fatty Acid Receptor (FFAR)-2CTAP
2CTAP

Chemical Structure : 2CTAP

CAS No.: 1229382-66-4

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2CTAP

货号: PC-20438Not For Human Use, Lab Use Only.

2CTAP is a small molecule inverse agonist of FFA2 receptor signalling, inhibits constitutive Ca2+ levels, antagonised acetate-induced pERK1/2 and prevents damage following IRI, has no effect on cAMP.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    2CTAP is a small molecule inverse agonist of FFA2 receptor signalling, inhibits constitutive Ca2+ levels, antagonised acetate-induced pERK1/2 and prevents damage following IRI, has no effect on cAMP.

    物理化学性质&存储条件

    分子量 386.85
    分子式 C19H15ClN2O3S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    4-((4-(2-chlorophenyl)thiazole-2-yl)amino)-4oxo-3-phenylbutanoic acid

    参考文献

    1. Zoe V Schofield, et al. Sci Rep. 2018 Dec 13;8(1):17819.

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