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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Estrogen Receptor/ERR-27-hydroxycholesterol
27-hydroxycholesterol

Chemical Structure : 27-hydroxycholesterol

CAS No.: 20380-11-4

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27-hydroxycholesterol (27HC, 27-OHC)

货号: PC-22707Not For Human Use, Lab Use Only.

27-Hydroxycholesterol (27-OHC, 27HC) is a selective estrogen receptor (ER) modulator and an agonist of the liver X receptor (LXR), regulates both gene transcription and cell proliferation in cellular models of breast cancer.

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5 mg ￥1580 In stock
10 mg ￥2480 In stock
25 mg ￥4280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

27-Hydroxycholesterol (27-OHC, 27HC) is a selective estrogen receptor (ER) modulator and an agonist of the liver X receptor (LXR), regulates both gene transcription and cell proliferation in cellular models of breast cancer.

物理化学性质&存储条件

分子量 402.66
分子式 C27H46O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(3S,8S,9S,10R,13R,14S,17R)-17-((2R,6R)-7-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

参考文献

1. Ye H, et al. Sci Adv. 2024 Jul 12;10(28):eadi4746.

2. DuSell CD, et al. Mol Endocrinol. 2008 Jan;22(1):65-77.

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