25B-NBOMe

Chemical Structure : 25B-NBOMe

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货号: PC-21178Not For Human Use, Lab Use Only.

25B-NBOMe is a highly selective 5-HT2A receptor agonist with Ki of 0.05 nM, 100-fold selective over 5-HT2C (Ki=4.6 nM).

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生物&药学活性

25B-NBOMe is a highly selective 5-HT2A receptor agonist with Ki of 0.05 nM, 100-fold selective over 5-HT2C (Ki=4.6 nM).
25B-NBOMe also has moderate affinity for the serotonin transporter (SERT, Ki=840 nM) and dopamine D2 receptors (Ki=840 nM), but its affinity for dopamine D1 receptor and dopamine transporter (DAT) is low.
25B-NBOMe in repeated doses induces tolerance in neurotransmitter release.
25B-NBOMe promotes anxiety in rats, shows genotoxic potential and increase in glial cells number.

物理化学性质&存储条件

分子量	380.28
分子式	C18H22BrNO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-Bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine

参考文献

1. Adam Wojtas, et al. Neuropharmacology. 2023 Sep 7;109713.

25B-NBOMe

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物理化学性质&存储条件

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25B-NBOMe

生物&药学活性

物理化学性质&存储条件

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