22-Azacholesterol (22-NHC)

Chemical Structure : 22-Azacholesterol

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货号: PC-62202Not For Human Use, Lab Use Only.

22-Azacholesterol is the first small molecule inhibitor that inhibits Hedgehog (Hh) signaling by binding the oxysterol-binding site of Smo, inhibits Sonic Hedgehog (Shh) signaling with IC50 of 3 uM in NIH-3T3 cells..

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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22-Azacholesterol (22-NHC) is the first small molecule inhibitor that inhibits Hedgehog (Hh) signaling by binding the oxysterol-binding site of Smo, inhibits Sonic Hedgehog (Shh) signaling with IC50 of 3 uM in NIH-3T3 cells.

物理化学性质&存储条件

分子量	387.64
分子式	C26H45NO
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	22-Azacholesterol

参考文献

1. Nedelcu D, et al. Nat Chem Biol. 2013 Sep;9(9):557-64.